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Victory Mile Walk

Get involved in victory walk | Scotland

Cumbernauld News | Original Link Scotland, United Kingdom —The Scottish Spina Bifida Association and North Lanarkshire Council are inviting people to take part in a one mile charity walk on Sunday, September 21. The Victory Mile Walk is organised as part of the Cumbernauld 10k event at Broadwood Stadium, which also includes 1k and 3k […]

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Hydro shunt issues

Hydrocephalus describes conditions in which the fluid in and around the brain, CSF, is trapped and causes high pressure. The pressure can harm the delicate brain tissue, so needs treating with a shunt to remove the fluid from the head, or a Third Vent…

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100 recent fetal surgeries for spina bifida performed at one American hospital

Science Daily | Original Link Press Release Source: Children’s Hospital of Philadelphia Summary Reporting on 100 recent cases of fetal surgery for spina bifida, specialists at a premier fetal surgery program achieved results similar to those published three years previously in a landmark clinical trial that established a new standard of care for prenatal repair […]

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Winnifred Connolly

The secret to being 99? Tea and laughs!

‘Was I behaving myself?’, Winnie asks with a mischievous grin. Winnie and her daughter Joyce are looking over some old photographs and the one in hand shows a group photo from Winnie’s 95th birthday party. Now aged 99, we believe Win…

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Lorraine Watson

Kamikaze gran set to skydive for charity Shine

Lorraine Watson, who will turn 70 next year, is set to skydive for the charity Shine in memory of her son on Saturday 30 August. Lorraine, who affectionately calls herself ‘Kamikaze Gran’ on her Just Giving page, has supported the charity …

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Figure 1: Computed tomography dorsal spine showing hemivertebra at D8, butterfly vertebra at D10 and absent ribs on left side

Rare association of spondylo costal dysostosis with split cord malformations type II: A case report and a brief review of literature

Journal of Pediatric Neurosciences | Original Link by Bhavanam Hanuma Srinivas1, Aneel Kumar Puligopu1, Dinesh Sukhla1, Prajnya Ranganath2 Abstract Spondylo costal dysostosis (SCD) is a genetic skeletal disorder characterized by a variety of costo-vertebral malformations. SCD with type I split cord malformation (SCM) have been reported in the literature. We report an unusual association of […]

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Figure 1. Summary of folate metabolism (simplified). The schematic diagram shows that after entry of synthetic FA or natural dietary folates through receptors/carriers in cell membrane, the intracellular folate/ FA pass through series of biochemical reactions, and alter DNA methylation. Abbreviations: DHFR, dihydrofolate reductase; DHF, dihydrofolate; THF, tetrahydrofolate; SHMT, serine-hydroxymethyltransferase; 5,10-methenyl- THF, 5,10-methenyl-tetrahydrofolate; MTHFR, 5,10-methylenetetrahydrofolate reductase; 5-methyl THF, 5-methyltetrahydrofolate; MS, methionine synthase; B12, vitamin B-12; SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine; DNMT, DNA methyltransferase; MT, methyltransferases.

Folic acid supplementation in pregnancy and implications in health and disease

Journal of Biomedical Science | Original Link by Subit Barua*, Salomon Kuizon and Mohammed A Junaid Abstract Maternal exposure to dietary factors during pregnancy can influence embryonic development and may modulate the phenotype of offspring through epigenetic programming. Folate is critical for nucleotide synthesis, and preconceptional intake of dietary folic acid (FA) is credited with […]

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